Abstract Human and animal studies suggest an intriguing link between mitochondrial diseases and depression. Although depression has historically been linked to alterations in monoaminergic pharmacology and adult hippocampal neurogenesis, new data increasingly implicate broader forms of dampened plasticity, including plasticity within the cell. Mitochondria are the cellular powerhouse of eukaryotic cells, and they also regulate […]
Photobiomodulation for the treatment of retinal diseases: a review
Abstract Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, Leber’s hereditary optic neuropathy, amblyopia, methanol-induced retinal damage, and possibly others. This review evaluates […]
The Beneficial Effects of Photobiomodulation to Reduce Intraocular Pressure in Primary Open-Angle Glaucoma
Abstract Purpose: The aim of this trail was to study the efficacy of photobiomodulation (PBM) treatment to reduce the intraocular pressure in subjects with primary open angle glaucoma disease. Methods: Twenty eyes suffering from open angle glaucoma with high IOP level were selected, examined and treated with Thera-RED light diode system. The subjects were divided into two […]
Visual red-light stimulation for improving sleep quality in older adults
Abstract Insomnia is one commonly reported sleep problem especially among older adults. Presently, it is treated by oral medicines. Since it has side effects, non-invasive therapies are one better alternative. Light in the band of 650 to 700 nm wavelength stimulate the production of melatonin. Hence red light is used in controlled mechanism to induce […]
Photobiomodulation Response From 660 nm is Different and More Durable Than That From 980 nm
A study examining the effects and mechanism of action of photobiomodulation (PBM) using two commonly employed wavelengths—660 nm red light and 980 nm infrared light—found that ~660 nm red light exposure led to a more prolonged stimulation of adenosine triphosphate (ATP) production. Related: Near Infrared Light Improves Fat Graft Viability Researchers at the Wellman Center for Photomedicine measured […]
Effect of Violet Light-Transmitting Eyeglasses on Axial Elongation in Myopic Children: A Randomized Controlled Trial
Abstract The fact that outdoor light environment is an important suppressive factor against myopia led us to invent violet light-transmitting eyeglasses (VL glasses) which can transmit violet light (VL), 360–400 nm in wavelength, for the suppression of myopia, and can meanwhile block harmful ultraviolet waves from sunlight. The current study is a double-blinded randomized clinical […]
Mitochondrial Dysfunction in the Aging Retina
Abstract Mitochondria are central in retinal cell function and survival and they perform functions that are critical to cell function. Retinal neurons have high energy requirements, since large amounts of ATP are needed to generate membrane potentials and power membrane pumps. Mitochondria over the course of aging undergo a number of changes. Aged mitochondria exhibit […]
Low-Level Light Therapy in the Treatment of Meibomian Gland Dysfunction
Abstract Purpose : Low-level light therapy (LLLT) is a growing modality used in various fields of medicine. This study observed the effect of LLLT on the tear film and lower eye lids in meibomian gland dysfunction (MGD) patients. Methods : The visual acuity (VA), lipid layer interference pattern (LP), non-invasive tear break up time (NIBUT), the lower eye lid-margins, […]
Effect of low-level light therapy in patients with dry eye: a prospective, randomized, observer-masked trial
Abstract To evaluate the efficacy of low-level light therapy (LLLT) with near-infrared light-emitting diodes (LED-LLLT) for the treatment of dry eye. 40 patients were randomly assigned with a 1:1 allocation ratio to receive LED-LLLT (LLLT group, n = 20) or placebo treatment (placebo group, n = 20). Patients in the LLLT group received LLLT twice a week for 3 […]
Photobiomodulation for Alzheimer’s Disease: Has the Light Dawned?
Abstract Next to cancer, Alzheimer’s disease (AD) and dementia is probably the most worrying health problem facing the Western world today. A large number of clinical trials have failed to show any benefit of the tested drugs in stabilizing or reversing the steady decline in cognitive function that is suffered by dementia patients. Although the […]