Abstract Purpose: To compare the treatment efficacy between repeated low-level red light (RLRL) therapy and 0.01% atropine eye drops for myopia control. Methods: A single-masked, single-center, randomized controlled trial was conducted on children 7 to 15 years old with cycloplegic spherical equivalent refraction (SER) ≤ -1.00 diopter (D) and astigmatism ≤ 2.50 D. Participants were randomly assigned […]
Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children: A Multicenter Randomized Controlled Trial
Abstract Purpose: To assess the efficacy and safety of repeated low-level red-light (RLRL) therapy in myopia control in children. Design: Multicenter, randomized, parallel-group, single-blind clinical trial. Participants: Two hundred sixty-four eligible children 8 to 13 years of age with myopia of cycloplegic spherical equivalent refraction (SER) of -1.00 to -5.00 diopters (D), astigmatism of 2.50 D or less, […]
Axial Shortening in Myopic Children after Repeated Low-Level Red-Light Therapy: Post Hoc Analysis of a Randomized Trial
Abstract Introduction: Axial length (AL) elongation in myopia is considered irreversible. We aimed to systemically report unexpected AL shortening observed in a randomized clinical trial (RCT) after repeated low-level red-light (RLRL) therapy. Methods: This is a post hoc analysis of a multicenter, single-masked RCT. Two hundred sixty-four myopic children aged 8-13 years allocated to RLRL treatment (intervention […]
A Study on the Effectiveness of 650-nm Red-Light Feeding Instruments in the Control of Myopia
Abstract Introduction: This study analyzed the effectiveness of 650-nm red-light feeding instruments in the control of myopia. Methods: In this study, 164 school-aged participants diagnosed with myopia in the city of Shenzhen were enrolled in a red-light feeding instrument study. Of these, 41 were enrolled in the mild-to-moderate myopia group that received red-light feeding (RLMM group), 65 […]
SIX YEARS FOLLOW-UP OF LOW-LEVEL LASER THERAPY (LLLT) IN PATIENTS WITH AGE-RELATED MACULAR DEGENERATION (AMD).
Purpose: The objective of this study is to examine long-term effects of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD). Methods: The research was implemented for a period of six years. For LLLT, a He-Ne Laser with continuous emission at 633 nm (01 mW/cm2) was used in patients with AMD of all […]
CLINICAL TRIAL DOWNLOAD: LIGHTSITE III 24-month Photobiomodulation Results
Photobiomodulation (PBM), previously referred to as low-level light therapy, has a 50-year history in medical research and has been investigated for treating a host of medical conditions. It is theorized that photons enter tissue and interact with enzyme cytochrome c oxidase located within mitochondria. Through an undefined mechanism, this is believed to increase cellular metabolism. […]
PHOTOBIOMODULATION THERAPY FOR LARGE SOFT DRUSEN AND DRUSENOID PIGMENT EPITHELIAL DETACHMENT IN AGE-RELATED MACULAR DEGENERATION: A Single-Center Prospective Pilot Study
Abstract Purpose: To evaluate visual acuity and morphologic changes after photobiomodulation (PBM) for patients affected with large soft drusen and/or drusenoid pigment epithelial detachment associated with dry age-related macular degeneration. Method: Twenty eyes with large soft drusen and/or drusenoid pigment epithelial detachment age-related macular degeneration were included and treated using the LumiThera Valeda Light Delivery System. All […]
Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
Abstract Purpose Photobiomodulation therapy (PBT) has emerged as a possible treatment for age-related macular degeneration (AMD) and diabetic retinopathy (DR). This review seeks to summarize the application of PBT in AMD and DR. Methods The National Clinical Trial (NCT) database and PubMed were queried using a literature search strategy and reviewed by the authors. Results […]
Photobiomodulation as a Treatment in Dry AMD
The development of innovative treatments for debilitating diseases such as age-related macular degeneration (AMD) is crucial to advance patient care and to reduce burdens on patients, caregivers, and physicians. The dry, or nonexudative, form of AMD affects approximately 85% to 90% of individuals with AMD, and, until now, there have been no approved treatments for […]
Five-year follow-up of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD)
Abstract The objective of this study was to examine long-term effects of low-level laser therapy (LLLT) in patients with age-related macular degeneration (AMD). The research was implemented for a period of five years. For LLLT, a He-Ne Laser with continuous emission at 633 nm (0.1 mW/cm2) was used in patients with AMD of all stages […]