Abstract Objective: This study investigated whether patients with mild to moderately severe dementia or possible Alzheimer’s disease (AD) with Mini-Mental State Exam (MMSE) Baseline scores of 10–24 would improve when treated with near-infrared photobiomodulation (PBM) therapy. Background: Animal studies have presented the potential of PBM for AD. Dysregulation of the brain’s default mode network (DMN) has been […]
Photobiomodulation therapy restores olfactory function impaired by photothrombosis in mouse olfactory bulb
Abstract An ischemic stroke typically accompanies numerous disorders ranging from somatosensory dysfunction to cognitive impairments, inflicting patients with various neurologic symptoms. Among pathologic outcomes, post-stroke olfactory dysfunctions are frequently observed. Despite the well-known prevalence, therapy options for such compromised olfaction are limited, likely due to the complexity of olfactory bulb architecture, which encompasses both the […]
Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression
Abstract Human and animal studies suggest an intriguing link between mitochondrial diseases and depression. Although depression has historically been linked to alterations in monoaminergic pharmacology and adult hippocampal neurogenesis, new data increasingly implicate broader forms of dampened plasticity, including plasticity within the cell. Mitochondria are the cellular powerhouse of eukaryotic cells, and they also regulate […]
Photobiomodulation Response From 660 nm is Different and More Durable Than That From 980 nm
A study examining the effects and mechanism of action of photobiomodulation (PBM) using two commonly employed wavelengths—660 nm red light and 980 nm infrared light—found that ~660 nm red light exposure led to a more prolonged stimulation of adenosine triphosphate (ATP) production. Related: Near Infrared Light Improves Fat Graft Viability Researchers at the Wellman Center for Photomedicine measured […]
Mitochondrial Dysfunction in the Aging Retina
Abstract Mitochondria are central in retinal cell function and survival and they perform functions that are critical to cell function. Retinal neurons have high energy requirements, since large amounts of ATP are needed to generate membrane potentials and power membrane pumps. Mitochondria over the course of aging undergo a number of changes. Aged mitochondria exhibit […]