Purpose : There are currently few treatment options available for the progression of RPE atrophy in non-exudative age-related macular degeneration (AMD). It is believed that individual oxidative stress, like in smoking, is a major clinical disease factor. In-vitro data demonstrate the protective anti-oxidative effect of photobiomodulation (PBM) when different wavelengths (in the visible and near-infrared range) of […]
Dry AMD therapy evolves with photobiomodulation
Take-home message: Non-invasive photobiomodulation may help dry age-related macular degeneration by causing regression of drusen and improving retinal function with benefits in visual acuity and contrast sensitivity. By Lynda Charters; Reviewed by Graham Merry, MBBS, and Marion R. Munk, MD, PhD Photobiomodulation (PBM) may be a new non-invasive, light- based treatment for patients with dry […]
Photobiomodulation reduces drusen volume and improves visual acuity and contrast sensitivity in dry age-related macular degeneration
Abstract Purpose To evaluate the efficacy of photobiomodulation (PBM) treatment for patients with dry age-related macular degeneration (AMD). Methods Assessments on 42 eyes with dry AMD (age related eye disease study (AREDS) 2–4) were conducted. Multiwavelength light emitting diode (LED) light comprising of yellow (590 nm), red (670 nm) and near-infrared (790 nm) bandwidths was applied to subjects’ […]
Photobiomodulation for the treatment of retinal diseases: a review
Abstract Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, Leber’s hereditary optic neuropathy, amblyopia, methanol-induced retinal damage, and possibly others. This review evaluates […]
Mitochondrial Dysfunction in the Aging Retina
Abstract Mitochondria are central in retinal cell function and survival and they perform functions that are critical to cell function. Retinal neurons have high energy requirements, since large amounts of ATP are needed to generate membrane potentials and power membrane pumps. Mitochondria over the course of aging undergo a number of changes. Aged mitochondria exhibit […]